Life Cycle Of Malarial Parasite (Plasmodium)

Hii friends, Today I am going to give you information about life cycle of malaria parasites.

Malaria –

  • The life cycle of the malarial parasite (Plasmodium) is complicated and involves two hosts, humans and female Anopheles mosquito.
  • The disease is transmitted to humans when an infected Anopheles mosquito bites a person and injected the malaria parasites (sporozoites) into the blood.
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  • Malaria is a mosquito -borne infection disease of humans caused by protist Plasmodium know as malaria parasite.
  • It is widespread in tropical and subtropical regions, including much of sub-saharmAfrica,Asia and America,
  • This malaria deases results are from the multiplication of malaria parasites in red blood cells and causing symptoms that typically include fever and headache in severe cases progressing to coma, and death.

There are four species of malaria parasites /Plasmodium can infect and be transmitted by humans. Server diseases is largely caused by

  • Plasmodium malariae
  • .Plasmodium vivax
  • Plasmodium ovale
  • Plasmodium falciparum.

How is malarial parasite transmitted?

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  • The life cycle of the malarial parasite (Plasmodium) is complicated and involves two hosts, humans and female Anopheles mosquito.
  • The disease is transmitted to humans when an infected Anopheles mosquito bites a person and injected the malaria parasites (sporozoites) into the blood.

Life cycle of malaria parasites in Anopheles mosquito

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  • Mosquitoes first ingest the malarial parasite while feeding on an infected human.
  • Once ingested, the gametocytes get differentiated into male or female gametes and fuse in the mosquitoes gut.
  • This produces an ookinete that penetrates the gut lining and products an oocyst in the gut wall.
  • When the oocyst ruptures,it releases sporozoites that migrate to the salivary glands. The sporozoites are injected into the skin, when the mosquito bites a normal person .
  • Only female mosquitoes feed on blood while male mosquitoes feed on plant sap, thus males do not spread the deases.


In the human body – life cycle of malaria parasites

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  • Malaria develops via two phases : an pereryotic and an erythrocytic phase.
  • The preerythrocytic phase involves infection of the liver.
  • On the red blood cells the erythrocytic phase involves infection
  • When mosquito bites a person, sporozoites enter the blood stream, and migrate to the liver.
  • The liver cells (hepatocytes) they infect ,where they multiply into merozoites.
  • They rupture the liver cell, and escape into the blood stream.
  • Then,merozoites infect red blood cells, where they develop into ring froms , trophozoites and then schizonts which in turn produce further merozoites.
  • Within the erythrocytes, the parasites multiply asexually, periodically breaking out of their hosts to invade fresh red blood cells.
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Signs and symptoms
Symptoms of malaria

  • Fever shivering
  • Arthragia (joint pain)
  • Vomiting
  • Anaemia
  • Hemoglobinuria
  • Retinal damage
  • Convulsions

Prevention

  • Malaria transmission can be reduced by preventing mosquito bites by mosquito nets and insect repellents, or by mosquito control measure such as spraying insecticides and draining standing water where mosquitoes lay their eggs.
  • The mosquito larvae can be controlled by realeas of Gambusia fish.

So guys, I hope you have understood the concept of life cycle of malaria parasites through this information. Share this information with your friends and family.

Thank you…!

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